Creutzfeldt-Jakob Disease (CJD) is a human prion disease that is a rapidly progressive neurodegenerative disorder that is universally fatal. There are three categories of CJD: Classical (sporadic or spontaneous), Familial, and Iatrogenic. Sporadic CJD is the most common form found in Arizona.
In Arizona in the last 10 years there have been 65 cases of CJD reported.
Arizona 5 year median: 8 cases
Transmission
Sporadic CJD occurs sporadically and there is no recognizable pattern of transmission. Familial CJD is thought to develop because of an inherited mutation of the prion protein gene. Iatrogenic CJD occurs as a result of exposure to infectious prions during a medical procedure. Corneal implants, Dura mater grafts, Brain surgery, and growth or Gonadotropic hormones made from human pituitary glands have all been implicated in iatrogenic CJD cases. Isolation PrecautionsCreutzfeldt-Jakob disease is not a communicable disease. Standard precautions are recommended in healthcare settings.
Prevention for Patients
Iatrogenic CJD can be prevented by correct sterilization of surgical equipment.
Public Health Actions
Public health will conduct an epidemiological investigation on a case or suspect case.
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